Zimu Huo

Zimu Huo

I’m interested in developing advanced data acquisition methods and reconstruction algorithms in magnetic resonance imaging (MRI).

EPI PEC-SENSE phase correction tutorial

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Due to the alternating direction of the EPI readout lines, hardware imperfections such as timing delays, eddy currents, and gradient coil heating can cause misalignment of the forward and reverse lines in k-space. This misalignment manifests itself in the images as a Nyquist (N/2) ghost in the phase encode direction and sinusoidal modulation of the object in the frequency encode direction.

The sampling incoherence is removed when interleving the positive and negative echos. However, a 2x acceleration is introduced to each dataset, resulting noise amplification

View the SENSE based EPI correction tutorial here

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Burst imaging simulation

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An ultrafast excitation and acquisition technique.

Simulatenous Mulit-slice reconstruction tutorial 5

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The slice-leakage is an artefact where the information from one slice is unintentionally transmitted to another slice during reconstruction. Any information from slice A that appears in slice B at the end of the reconstruction is considered slice leakage. The current method involves using a Monte Carlo simulation to impose unique frequency modulations on each slice. After reconstructions, the slice leakage can be determined by quantifying the frequency modulations on each individual slice. For example, if we add a 4 Hz modulation on slice A and a 6 Hz modulation on slice B, any 6 Hz component found on slice A after the reconstruction could be used to indicate slice leakage.

NUFFT tutorial

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Challenges arise when reconstructing from non-uniform sampling patterns in the Fourier domain. Performing a direct Fourier transform in such cases incurs a quadratic computation cost of O($N^2$), rendering it impractical for standard practices at high resolutions. This requires transforming non-Cartesian samples back into a uniformly spaced Cartesian grid, enabling the utilization of more efficient FFT algorithms. Typical regridding procedures involve convolving the acquired data with a predefined gridding kernel weighted by the pre-calculated density compensation function, followed by a resampling process onto the Cartesian grid. The ideal gridding kernel is a sinc function, as its Fourier transform results in a rectangular function. However, since the optimal convolution function is of infinite extent, implementing it directly is impractical. To address this, the convolution kernel is truncated and windowed. A popular choice for this purpose is the use of Kaiser-Bessel functions. These methodologies are commonly known as “gridding” and is a special case of non-uniform Fourier transforms (NUFFT).

bSSFP simulation tutorial 2

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Here, I present various variations of bSSFP: standard bSSFP, fluctuating equilibrium, and alternating steady states. Each variation manipulates sequence parameters such as TR, flip angles, and RF phase to generate unique profiles optimized for specific tasks.